Alzheimer's Disease and Suicide: An Integrative Literature Review.

INTRODUCTION: Suicide has been described in patients with Alzheimer's disease. Some promising medications for treating Alzheimer's disease have had their studies suspended because they increase the risk of suicide. Understanding the correlations between suicide and Alzheimer's disease is essential in an aging world. METHOD: A search was carried out on electronic websites (PubMed and Scielo) using the MeSH Terms "suicide" and "Alzheimer" (1986-2023). Of a total of 115 articles, 26 were included in this review. RESULTS: Depression and the allele ε4 of Apolipoprotein (APOE4) were demonstrated to be the main risk factors for suicide in patients with Alzheimer's disease. CONCLUSION: Adequately delineating which elderly people are vulnerable to suicide is important so that new treatments for Alzheimer's disease can be successful. This review showed a need for new studies to investigate the interface between Alzheimer's disease and suicide.

Development and validation of a questionnaire to measure association factors with suicide: An instrument for a populational survey.

Background and Aims: Our goal was to develop an online questionnaire to survey the prevalence of suicidal behavior. Methods: We developed a questionnaire with 51 variables and proceeded with validations. Validations were performed using face validity, content validity, and construct validity. Reliability was performed by test-rest. Results: The face validity was 1.0 and the content validity was 0.91. The exploratory factor analysis got Kaiser-Meyer-Olkin = 0.86 and extracted one principal factor. The confirmatory factor analysis demonstrates root mean square error of approximation = 0.000 and comparative fit index = 1.000. The test-retest had an intraclass correlated coefficient of 0.98. Conclusion: The adequate development questionnaire was validated, and we have an instrument to survey suicide behaviors during the pandemic time. Patient or Public Contribution: The general population of Marília voluntarily responded to the questionnaire, as well as patients from the principal investigator's office.

Nem só de falta de recursos padece o SUS: uma crítica à tomada de decisöes clínicas / Not all that hampers the unified health system is money shortage: a criticism on clinical decision taking

Os autores relatam o trajeto de um paciente através do Sistema Público de Saúde em Juiz de Fora - Brasil, até o diagnóstico final de Diabetes Mellitus tipo 1. Decisöes clínicas näo adequadas nos diferentes níveis de atençäo säo realçadas como um fator contribuinte para a baixa resolutividade do sistema.